Reactive oxygen species (ROS) or oxidative stress has been reported with strongly involving to pathogenesis of many diseases in human. On the other hand, ROS play a critical regulation as secondary signal to maintain intracellular redox equilibrium. Basically, the antioxidant defense systems in the body counteract with overproduced ROS. However, when the redox balance is broken under severe oxidative stress conditions, it leads to tissue injuries and numerous disorders. In this review, we briefly introduce the systems of ROS and antioxidants systems in the body and discuss the opposite roles of ROS in normal physiological conditions and diseases. For ROS-related diseases, conventional and currently developed antioxidant therapies are also described in this review.
Roles of Reactive Oxygen Species in Diseases and Development of Novel Antioxidant Therapeutics
Review- Long Binh Vong, Nhu-Thuy Trinh, Dai-Nghiep Ngo,
- Pages 1-6
- 29/11/2018
- 60
- 405
- Free
Graphical abstract
Issue 1, 2017, Letter from President of UMP Issue 2, 2018, Prevalence of Sick Building Syndrome - Related Factors among Hospital Workers at University Medical Center Ho Chi Minh City, Vietnam Issue 1, 2017, Quantitative Hepatitis B Surface Antigen in Different Phases of Chronic HBV Infection in Vietnamese Patients: The Preliminary Study Issue 1, 2017, The Incidence and Characteristics of Gastrointestinal Intolerance on Mechanically Ventilated Patients with Continuous versus Intermittent Feeding Method in The Intensive Care Unit: A Randomized Controlled Trial Issue 2, 2018, Predictive Model for Live Birth at 12 Months After Starting In-Vitro Fertilization Treatment
Issue 3, 2018, Directed Acyclic Graphs: Alternative tool for causal inference in epidemiology and biostatistics research and teaching Issue 2, 2018, Prevalence of Sick Building Syndrome - Related Factors among Hospital Workers at University Medical Center Ho Chi Minh City, Vietnam Issue 1, 2017, Virtual Screening, Oriented-synthesis and Evaluation of Lipase Inhibitory Activity of Benzyl Amino Chalcone Derivatives Issue 1, 2017, The Incidence and Characteristics of Gastrointestinal Intolerance on Mechanically Ventilated Patients with Continuous versus Intermittent Feeding Method in The Intensive Care Unit: A Randomized Controlled Trial Issue 1, 2017, Quantitative Hepatitis B Surface Antigen in Different Phases of Chronic HBV Infection in Vietnamese Patients: The Preliminary Study